Vol. 3, Issue 11 (2015)

Author(s):
Dr. Kavita Arora

Abstract:
An evaluation of the toxic effects of the organophosphate, monocrotophos, was made by the histochemical and biochemical studies of general lipids in the rat liver after treatment with its low residual level doses (LD50 1.4 mg/kg) to three groups TI, TII & R of six rats each for 15 days, 30 days and 30 days with recovery period of 15 days respectively. The treated groups TI & TII showed significant increase in lipids in hepatic cells and significant decrease in triglycerides in serum whereas in R group showed significant recovery. The observations are thus indicative of the hepatic toxicity caused by organophosphates at cellular level in the liver of rats.