Vol. 3, Issue 9 (2014)

Author(s):
Nadbrodna Olga

Abstract:
The liver is one of the main organs for the regulation of carbohydrate, protein and lipid metabolism, glycogen deposition. Metabolic disorders in MS are always accompanied by changes in liver function. We have investigated the protein, lipid and carbohydrate profile of blood of 120 patients (divided into 3 groups) with nonalcoholic steatohepatitis in conjunction with the pathology of the gallbladder: calculous cholecystitis(1st group), non-calculous cholecystitis (2nd group); or without pathology of gallbladder (3rd group) to assess changes in metabolism and possible future clinical and functional changes specific to the presence of combined pathology. We discovered that gallstone disease affects the course of nonalcoholic steatohepatitis and accompanied by decompensation of carbohydrate, protein and lipid metabolism, as in patients of the third study group changes in clinical and laboratory parameters were the most insignificant compared to first group and second group.