Vol. 3, Issue 6 (2014)
State of protein peroxidation in newborns with intrauterine growth restriction
Kocherha Z.R., Ersteniuk H.M., Kovalchuk L.Ye
The main study group involved 56 newborns with intrauterine growth restriction (IUGR) The comparison group included 52 healthy newborns. It has been proved that in newborns with IUGR the levels of neutral-type aldehyde- and ketone derivatives with peak absorption at wavelengths of 356 and 370 nm were higher, as compared to healthy newborns (р<0.05), namely 1.74±0.08 and 1.58±0.13. The basic-type aldehyde-and ketone derivatives had a tendency to increase in healthy newborns as compared with IUGR newborns. The determination of protein oxidative modifications of basic and neutral-type aldehyde- and ketone derivatives in combination with clinical findings are recommended for establishing the prognosis of the severity of hypoxic CNS damage in newborns with IUGR.
How to cite this article:
Kocherha Z.R., Ersteniuk H.M., Kovalchuk L.Ye. . The Pharma Innovation Journal. 2014; 3(6): 09-12.