Vol. 2, Issue 9 (2013)
Antidermatophytic activity of Apamarga-Mulaka Seeds specific to Sidhma (Pityriasis versicolor) in children - A clinical study
Khatri Ravi Shankar, Singh B.M., Tilak Ragini, Singh Girish
Background: Apamarga (Achyranthes aspera Linn.) and Mulaka (Raphenus sativusLinn.) drugs are being used by Ayurveda to cure the Sidhma (~Pityriasisversicolor) for many centuries in children. Objective: To assess the comparative effect of 10% glycerin preparation-Apamarga and Mulaka Seeds’ dried water extract and-1% clotrimazole lotion in Sidhma (Pityriasis versicolor) disease affected children, aged from 1-16 years irrespective to sex. Material & Method: A total of 40 cases, of both sex of Sidhma (Pityriasis versicolor) were taken and randomly allocated, irrespective to severity of disease, into – a trial group -A (n=20) and another control group-B (n=20) based on the 10% glycerin based trial drug Apamarga-Mulaka Seeds dried water extract and control drug-1% clotrimazole lotion applied over the skin lesion, respectively, for 42 days. Skin lesion characteristics of both groups were observed at first, second, third and fourth follow up. Observation and Results: The analysis of gathered data in respect to types and distribution of rashes, color of rashes, size of rashes, itching and scaling of Pityriasisversicolor lesions in children shows statistically significant (<0.001) effect in trial group when compared to the control group drug on 1st & subsequent follow up. During the study period, no adverse effect was noted. Conclusion: Early & significant effect of the trial drug suggests its safer and effective use in treatment of Sidhma (Pityriasis versicolor).
How to cite this article:
Khatri Ravi Shankar, Singh B.M., Tilak Ragini, Singh Girish. . The Pharma Innovation Journal. 2013; 2(9): 41-47.