Vol. 1, Issue 11 (2013)

Author(s):
Sunil Kumar, D. P. Pathak

Abstract:
A series of acetylnaphthalene and substituted acetylnaphtahlene have been prepared by mannich reaction with four different secondary amine compounds and formandehyde. In this reaction Acetyl gruoup of acetyl naphthalene and substituted acetylnaphthalene have been used as hydrogen active compound. The structures of new compounds have been confirmed by spectral data. The novel compounds were tested for anticonvulsant activity using pentylenetetrazole (scPTZ) test. Among the tested some acetylnaphthalene and substituted acetyl naphthalene derivatives of heterocyclic compounds were show significant anticonvulsant activity.